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Robert H. Eibl (born in 1964 in Bad Reichenhall, Bavaria, Germany) M.D. is a german tumor biologist and biophysicist.

Eibl obtained his M.D. from the University of Heidelberg working as a molecular and cellular biologist at the German Cancer Research Center. With Paul Kleihuesand Otmar D. Wiestler at the university hospital of Zurich, Switzerland, Eibl developed a model for childhood brain tumors, such as medulloblastomas and PNETs [1]. Eibl co-authored several highly cited papers on p53 mutations in different types of brain tumors, and he was the first to detect p53 mutations in low-grade astrocatomas (WHO grade II).
At Stanford University Eibl compared leukocyte homing with the steps involved in organ-specific metastasis (officially sponsored by Irving Weissman and with the lab of Eugene C. Butcher). Eibl combined his findings and training from Stanford University on cell adhesion receptors, such as VLA-4/VCAM-1 and SDF-1, with nanotechnology and became the first scientist to measure on a single-molecule level the physiologic activation of any integrin by any chemokine - on an intact and living cell[2][3]. He currently authors several papers and book chapters with these new and detailed methods[4][5].

In 2006 Eibl was included in Marquis' Who's Who in Medicine and Healthcare and was selected in 2008 for inclusion in Marquis' Who's Who in the World.

References

  1. ^ Eibl RH, Kleihues P, Jat PS, Wiestler OD: A model for primitive neuroectodermal tumors in transgenic neural transplants harboring the SV40 large T antigen. In: Am J Pathol 1994;144(3):556-64
  2. ^ R. H. Eibl, First measurement of physiologic VLA-4 activation by SDF-1 at the single-molecule level on a living cell. In: Advances in Single Molecule Research for Biology and Nanoscience. Hinterdorfer P, Schuetz G, Pohl P (Editors),Trauner, ISBN (2006)
  3. ^ Eibl RH, Benoit M, Molecular resolution of cell adhesion forces, IEE - Nanobiotechnology 151(3):128-132 (2004), ISSN: 1478-1581
  4. ^ Eibl RH and Moy VT, Atomic force microscopy measurements of protein-ligand interactions on living cells, In: Protein-Ligand Interactions (Editor: G.Ulrich Nienhaus), Humana Press, Totowa, NJ, U.S.A., pp. 437-448 (2005)
  5. ^ Robert H. Eibl: Direct Force Measurements of Receptor-Ligand Interactions on Living Cells In: Applied Scanning Probe Methods. Bhushan B, Fuchs H, Tomitori M (editors), Springer, Heidelberg (in press)

Source: http://en.wikipedia.org/wiki/Robert_Eibl



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